' 
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 3 Reviews
8.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Folate (400 mcg as (6S)-5-MTHF [(6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFE‡
170%
Top Medical Research Studies
7
Folic acid reduces cholesterol risk
Genetically predicted lipid traits mediate the association between folic acid and atherosclerosis.
Moderate relevance to cholesterol effects
We set out to understand how folic acid (FA) levels relate to high cholesterol and the risk of atherosclerosis, a leading cause of heart disease. Utilizing a method called Mendelian randomization, which leverages genetic data to uncover causal relationships, we explored the connection between genetically determined FA levels and atherosclerosis risk.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Read More
8
Cholesterol reduction in children studied
Beneficial Effects of a Nutraceutical Combination on Lipid Profiles in Children with Moderate and Severe Hypercholesterolemia.
Folate's individual impact unclear
We investigated how a special dietary supplement, which includes folate among other natural components, impacts cholesterol levels in children and adolescents with moderate to severe hypercholesterolemia. The supplement, called Armolipid, combines red yeast rice, policosanols, coenzyme Q10, astaxanthin, and folic acid.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Read More
Most Useful Reviews
9.5
Reduced homocysteine levels
My blood tests revealed elevated homocysteine, which can indicate poor lifestyle choices and heightens the risk of heart and vascular issues. I discovered I have folic acid malabsorption, so I was prescribed Methylfolate instead. After 2 weeks of taking 4000 mcg daily, my homocysteine dropped from 14 to 5.8. I now take 800 mcg per day.
Read More
9.5
Supports fetal health
My gynaecologist recommended folic acid during pregnancy, but I learned that methylfolate is better absorbed. This vitamin is crucial for the fetus's development and heart health. Taking it before and during pregnancy can reduce the risk of brain and spine defects. The capsules are small, easy to take, and tasteless. I've ordered it multiple times and am pleased with the results.
Read More
9.5
Lowered cholesterol levels
I chose this supplement for its dosage of 680 mcg, taking it alongside omega 3 and vitamin D3 to improve heart function and reduce high cholesterol. After two months, my cholesterol dropped from 5.8 mmol/L to 5.03 mmol/L, which is a normal level. I'm satisfied with the outcome and plan to continue after a break, although it's synthetic rather than plant-based.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
8
Cholesterol reduction in children studied
Beneficial Effects of a Nutraceutical Combination on Lipid Profiles in Children with Moderate and Severe Hypercholesterolemia.
Folate's individual impact unclear
We investigated how a special dietary supplement, which includes folate among other natural components, impacts cholesterol levels in children and adolescents with moderate to severe hypercholesterolemia. The supplement, called Armolipid, combines red yeast rice, policosanols, coenzyme Q10, astaxanthin, and folic acid.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Read More
7
Folic acid reduces cholesterol risk
Genetically predicted lipid traits mediate the association between folic acid and atherosclerosis.
Moderate relevance to cholesterol effects
We set out to understand how folic acid (FA) levels relate to high cholesterol and the risk of atherosclerosis, a leading cause of heart disease. Utilizing a method called Mendelian randomization, which leverages genetic data to uncover causal relationships, we explored the connection between genetically determined FA levels and atherosclerosis risk.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Our findings revealed that higher FA levels are linked to a lower risk of atherosclerosis. Specifically, we observed that individuals with greater FA levels had favorable cholesterol profiles—showing higher levels of good cholesterol (HDL-C) and lower levels of bad cholesterol (LDL-C) and triglycerides (TG). This suggests that FA might exert a protective effect on heart health by improving lipid levels.
Interestingly, we found that LDL-C, HDL-C, and TG together mediate a notable portion of this relationship, accounting for just over 13% of the total impact of FA on atherosclerosis. In simpler terms, improving cholesterol could be a significant part of how folic acid helps reduce heart disease risk.
Overall, this study emphasizes the importance of maintaining healthy folate levels, as it can be a vital step in reducing cholesterol and, consequently, lowering cardiovascular risks.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.7
9.5
Reduced homocysteine levels
My blood tests revealed elevated homocysteine, which can indicate poor lifestyle choices and heightens the risk of heart and vascular issues. I discovered I have folic acid malabsorption, so I was prescribed Methylfolate instead. After 2 weeks of taking 4000 mcg daily, my homocysteine dropped from 14 to 5.8. I now take 800 mcg per day.
Read More
9.5
Supports fetal health
My gynaecologist recommended folic acid during pregnancy, but I learned that methylfolate is better absorbed. This vitamin is crucial for the fetus's development and heart health. Taking it before and during pregnancy can reduce the risk of brain and spine defects. The capsules are small, easy to take, and tasteless. I've ordered it multiple times and am pleased with the results.
Read More
9.5
Lowered cholesterol levels
I chose this supplement for its dosage of 680 mcg, taking it alongside omega 3 and vitamin D3 to improve heart function and reduce high cholesterol. After two months, my cholesterol dropped from 5.8 mmol/L to 5.03 mmol/L, which is a normal level. I'm satisfied with the outcome and plan to continue after a break, although it's synthetic rather than plant-based.
Read More
